Postdoctoral Training Fellow – Computational Biology

Competitive with benefits, subject to skills and experience
01 Nov 2018
02 Dec 2018
Contract Type
Full Time

An exciting opportunity for a Computational Biology Postdoctoral Training Fellow is available in James Turner’s lab. The lab is a highly interactive group of ten staff, including postdocs, PhD students, and technicians, that work on the mammalian sex (X and Y) chromosomes. We research areas including X-chromosome inactivation, germ cell and embryo development, sex chromosome evolution and stem cell biology, with the principle aim being to develop more personalised disease therapies for men and women. Research in the lab is funded by the ERC, MRC, Wellcome, CRUK and AstraZeneca. Several projects related to sex chromosome biology are available. Examples include deciphering the effects of aneuploidy and DNA damage on the embryonic epigenome, and understanding how evolution has shaped the gene content of the mammalian X chromosome. The applicant will use state-of-the-art single cell transcriptomics, methylomics and genomics datasets from humans, mice and unusual model organisms, including marsupials. The applicant will take a lead role in their project, to collaborate within the team and foster collaborations, teach junior members of the team and interact with other members of the institute. Opportunities to carry out wet lab are also available.

Project scope

Some of the specific aims for this role are, but not limited to:

  • Investigating research questions and developing specific research project(s) under guidance from Group Leader
  • Providing specialist advice and guidance, sharing knowledge and expertise for the benefit of others
  • Providing significant contribution to the production of research papers for publication, presenting findings to group members and other internal audiences
  • Presenting work externally at international meetings
  • Authoring papers under guidance from Group Leader
  • Following Postdoctoral Training programme
  • Developing academic independence
  • Improving established protocols and/or develops new protocols
  • May be required to guide others

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

  • If you are interested in applying for this role, please apply via our website.
  • The closing date for applications is 02 December 2018 at 23:30.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.